Design, Synthesis, Kinetic Analysis and Pharmacophore-Directed Discovery of 3-Ethylaniline Hybrid Imino-Thiazolidinone as Potential Inhibitor of Carbonic Anhydrase II: An Emerging Biological Target for Treatment of Cancer

Carbonic anhydrases (CA), having Zn(2+) metal atoms, are responsible for the catalysis of CO(2) and water to bicarbonate and protons. Any abnormality in the functioning of these enzymes may lead to morbidities such as glaucoma and different types of cancers including brain, renal and pancreatic carc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmed, Atteeque, Aziz, Mubashir, Ejaz, Syeda Abida, Channar, Pervaiz Ali, Saeed, Aamer, Zargar, Seema, Wani, Tanveer A., Hamad, Asad, Abbas, Qamar, Raza, Hussain, Kim, Song Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687900/
https://www.ncbi.nlm.nih.gov/pubmed/36421710
http://dx.doi.org/10.3390/biom12111696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687900/
https://www.ncbi.nlm.nih.gov/pubmed/36421710
http://dx.doi.org/10.3390/biom12111696

Ejemplares similares