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Structural Consequences of Deproteinating the 50S Ribosome

Ribosomes are complex ribonucleoprotein particles. Purified 50S ribosomes subjected to high-salt wash, removing a subset of ribosomal proteins (r-proteins), were shown as competent for in vitro assembly into functional 50S subunits. Here, we used cryo-EM to determine the structures of such LiCl core...

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Detalles Bibliográficos
Autores principales: Larsson, Daniel S. D., Kanchugal P, Sandesh, Selmer, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687910/
https://www.ncbi.nlm.nih.gov/pubmed/36358955
http://dx.doi.org/10.3390/biom12111605