An Innovative PTD-IVT-mRNA Delivery Platform for CAR Immunotherapy of ErbB(+) Solid Tumor Neoplastic Cells

Chimeric antigen receptor (CAR) immunotherapy includes the genetic modification of immune cells to carry such a receptor and, thus, recognize cancer cell surface antigens. Viral transfection is currently the preferred method, but it carries the risk of off-target mutagenicity. Other transfection pla...

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Detalles Bibliográficos
Autores principales: Georgiou-Siafis, Sofia K., Miliotou, Androulla N., Ntenti, Charikleia, Pappas, Ioannis S., Papadopoulou, Lefkothea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687928/
https://www.ncbi.nlm.nih.gov/pubmed/36359405
http://dx.doi.org/10.3390/biomedicines10112885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687928/
https://www.ncbi.nlm.nih.gov/pubmed/36359405
http://dx.doi.org/10.3390/biomedicines10112885

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