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Combined DiI and Antibody Labeling Reveals Complex Dysgenesis of Hippocampal Dendritic Spines in a Mouse Model of Fragile X Syndrome

Structural, functional, and molecular alterations in excitatory spines are a common hallmark of many neurodevelopmental disorders including intellectual disability and autism. Here, we describe an optimized methodology, based on combined use of DiI and immunofluorescence, for rapid and sensitive cha...

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Detalles Bibliográficos
Autores principales:	Speranza, Luisa, Filiz, Kardelen Dalım, Goebel, Sarah, Perrone-Capano, Carla, Pulcrano, Salvatore, Volpicelli, Floriana, Francesconi, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687937/ https://www.ncbi.nlm.nih.gov/pubmed/36359212 http://dx.doi.org/10.3390/biomedicines10112692

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