Non-Selective PDE4 Inhibition Induces a Rapid and Transient Decrease of Serum Potassium in Mice

SIMPLE SUMMARY: Inhibitors of phosphodiesterase 4 (PDE4), a group of isoenzymes that hydrolyze and inactivate the second messenger cAMP, produce promising therapeutic benefits, including anti-inflammatory and memory-enhancing effects. Here, we report that, unexpectedly, PDE4 inhibitors also reduce s...

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Detalles Bibliográficos
Autores principales: Boyd, Abigail, Lochmaier, Peter, Irelan, Daniel, Fiedler, Edward, Lee, Ji Young, Fouty, Brian, Abou Saleh, Lina, Richter, Wito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687940/
https://www.ncbi.nlm.nih.gov/pubmed/36358283
http://dx.doi.org/10.3390/biology11111582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687940/
https://www.ncbi.nlm.nih.gov/pubmed/36358283
http://dx.doi.org/10.3390/biology11111582

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