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Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins

Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable side effects. However, it possesses a very low water solubility that can affect its oral bioavailability. In thi...

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Detalles Bibliográficos
Autores principales: De Gaetano, Federica, Cristiano, Maria Chiara, Paolino, Donatella, Celesti, Consuelo, Iannazzo, Daniela, Pistarà, Venerando, Iraci, Nunzio, Ventura, Cinzia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687945/
https://www.ncbi.nlm.nih.gov/pubmed/36421730
http://dx.doi.org/10.3390/biom12111716