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Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins
Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable side effects. However, it possesses a very low water solubility that can affect its oral bioavailability. In thi...
Autores principales: | De Gaetano, Federica, Cristiano, Maria Chiara, Paolino, Donatella, Celesti, Consuelo, Iannazzo, Daniela, Pistarà, Venerando, Iraci, Nunzio, Ventura, Cinzia Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687945/ https://www.ncbi.nlm.nih.gov/pubmed/36421730 http://dx.doi.org/10.3390/biom12111716 |
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