PTC124 Rescues Nonsense Mutation of Two Tumor Suppressor Genes NOTCH1 and FAT1 to Repress HNSCC Cell Proliferation

(1) Background: PTC124 (Ataluren) is an investigational drug for the treatment of nonsense mutation-mediated genetic diseases. With the exception of the TP53 tumor suppressor gene, there has been little research on cancers with nonsense mutation. By conducting a database search, we found that anothe...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Han, Lu, Rui-Yu, Yu, Si-Jie, Tsai, Yi-Zhen, Lin, Ying-Chen, Bai, Zhi-Yu, Liao, Ruo-Yu, Hsu, Yi-Chiang, Chen, Chia-Chi, Cai, Bi-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687978/
https://www.ncbi.nlm.nih.gov/pubmed/36428516
http://dx.doi.org/10.3390/biomedicines10112948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687978/
https://www.ncbi.nlm.nih.gov/pubmed/36428516
http://dx.doi.org/10.3390/biomedicines10112948

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