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Macrophage-Targeted Sodium Chlorite (NP001) Slows Progression of Amyotrophic Lateral Sclerosis (ALS) through Regulation of Microbial Translocation

Amyotrophic lateral sclerosis (ALS) is a heterogeneous, progressive, and universally fatal neurodegenerative disease. A subset of ALS patients has measurable plasma levels of lipopolysaccharide (LPS) and C-reactive protein (CRP) consistent with low-grade microbial translocation (MT). Unless interrup...

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Detalles Bibliográficos
Autores principales: Zhang, Rongzhen, Bracci, Paige M., Azhir, Ari, Forrest, Bruce D., McGrath, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687998/
https://www.ncbi.nlm.nih.gov/pubmed/36428474
http://dx.doi.org/10.3390/biomedicines10112907