Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia

Fibrillar amyloid β-protein (Aβ) deposits in the brain, which are primarily composed of Aβ40 or Aβ42 peptides, are key pathological features of Alzheimer’s disease (AD) and related disorders. Although the underlying mechanisms are still not clear, the Aβ fibrils can trigger a number of cellular resp...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyue, Schrader, Joseph M., Irizarry, Brandon A., Smith, Steven O., Van Nostrand, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688026/
https://www.ncbi.nlm.nih.gov/pubmed/36428550
http://dx.doi.org/10.3390/biomedicines10112982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688026/
https://www.ncbi.nlm.nih.gov/pubmed/36428550
http://dx.doi.org/10.3390/biomedicines10112982

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