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Maximum Somatic Allele Frequency-Adjusted Blood-Based Tumor Mutational Burden Predicts the Efficacy of Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Recent studies exhibited the unstable prediction ability of blood-based tumor mutational burden (bTMB) when predicting the response of immune checkpoint inhibitors (ICIs) therapy in patients with non-small cell lung cancer (NSCLC). Circulating tumor DNA (ctDNA) abundance, usually rep...

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Detalles Bibliográficos
Autores principales: Dong, Yiting, Zhu, Yixiang, Zhuo, Minglei, Chen, Xiaomin, Xie, Yinpeng, Duan, Jianchun, Bai, Hua, Hao, Shiguang, Yu, Zicheng, Yi, Yuting, Guan, Yanfang, Yuan, Jie, Xia, Xuefeng, Yi, Xin, Wang, Jie, Wang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688065/
https://www.ncbi.nlm.nih.gov/pubmed/36428744
http://dx.doi.org/10.3390/cancers14225649