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Inactivation of Autophagy in Keratinocytes Reduces Tumor Growth in Mouse Models of Epithelial Skin Cancer

Autophagy is a ubiquitous degradation mechanism, which plays a critical role in cellular homeostasis. To test whether autophagy suppresses or supports the growth of tumors in the epidermis of the skin, we inactivated the essential autophagy gene Atg7 specifically in the epidermal keratinocytes of mi...

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Detalles Bibliográficos
Autores principales: Barresi, Caterina, Rossiter, Heidemarie, Buchberger, Maria, Pammer, Johannes, Sukseree, Supawadee, Sibilia, Maria, Tschachler, Erwin, Eckhart, Leopold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688105/
https://www.ncbi.nlm.nih.gov/pubmed/36429119
http://dx.doi.org/10.3390/cells11223691