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Fatty Acid Synthase Mutations Predict Favorable Immune Checkpoint Inhibitor Outcome and Response in Melanoma and Non-Small Cell Lung Cancer Patients

SIMPLE SUMMARY: A key point in immunotherapies is to determine tumor cases that are sensitive to immune checkpoint inhibitors (ICI). Effective indicators could accurately evaluate the ICI treatment efficacy. Fatty acid synthase (FASN) is frequently mutated in tumor genomes. In this work, we consolid...

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Detalles Bibliográficos
Autores principales: Wang, Qinghua, Tian, Na, Zhang, Wenjing, Lin, Zhijuan, Shi, Fuyan, Kong, Yujia, Ren, Yanfeng, Lyu, Juncheng, Qin, Hao, Liu, Hongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688165/
https://www.ncbi.nlm.nih.gov/pubmed/36428733
http://dx.doi.org/10.3390/cancers14225638