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Fatty Acid Synthase Mutations Predict Favorable Immune Checkpoint Inhibitor Outcome and Response in Melanoma and Non-Small Cell Lung Cancer Patients
SIMPLE SUMMARY: A key point in immunotherapies is to determine tumor cases that are sensitive to immune checkpoint inhibitors (ICI). Effective indicators could accurately evaluate the ICI treatment efficacy. Fatty acid synthase (FASN) is frequently mutated in tumor genomes. In this work, we consolid...
Autores principales: | Wang, Qinghua, Tian, Na, Zhang, Wenjing, Lin, Zhijuan, Shi, Fuyan, Kong, Yujia, Ren, Yanfeng, Lyu, Juncheng, Qin, Hao, Liu, Hongqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688165/ https://www.ncbi.nlm.nih.gov/pubmed/36428733 http://dx.doi.org/10.3390/cancers14225638 |
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