Search for Synergistic Drug Combinations to Treat Chronic Lymphocytic Leukemia

Finding synergistic drug combinations is an important area of cancer research. Here, we sought to rationally design synergistic drug combinations with an inhibitor of BTK kinase, ibrutinib, which is used for the treatment of several types of leukemia. We (a) used a pooled shRNA screen to identify ge...

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Detalles Bibliográficos
Autores principales: Hezkiy, Eleonora Ela, Kumar, Santosh, Gahramanov, Valid, Yaglom, Julia, Hesin, Arkadi, Jadhav, Suchita Suryakant, Guzev, Ekaterina, Patel, Shivani, Avinery, Elena, Firer, Michael A., Sherman, Michael Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688317/
https://www.ncbi.nlm.nih.gov/pubmed/36429097
http://dx.doi.org/10.3390/cells11223671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688317/
https://www.ncbi.nlm.nih.gov/pubmed/36429097
http://dx.doi.org/10.3390/cells11223671

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