Construction of a Versatile, Programmable RNA-Binding Protein Using Designer PPR Proteins and Its Application for Splicing Control in Mammalian Cells

RNAs play many essential roles in gene expression and are involved in various human diseases. Although genome editing technologies have been established, the engineering of sequence-specific RNA-binding proteins that manipulate particular cellular RNA molecules is immature, in contrast to nucleotide...

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Detalles Bibliográficos
Autores principales: Yagi, Yusuke, Teramoto, Takamasa, Kaieda, Shuji, Imai, Takayoshi, Sasaki, Tadamasa, Yagi, Maiko, Maekawa, Nana, Nakamura, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688318/
https://www.ncbi.nlm.nih.gov/pubmed/36428958
http://dx.doi.org/10.3390/cells11223529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688318/
https://www.ncbi.nlm.nih.gov/pubmed/36428958
http://dx.doi.org/10.3390/cells11223529

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