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Paraoxonase 2 (PON2) Deficiency Reproduces Lipid Alterations of Diabetic and Inflammatory Glomerular Disease and Affects TRPC6 Signaling

Diabetes and inflammatory diseases are associated with an altered cellular lipid composition due to lipid peroxidation. The pathogenic potential of these lipid alterations in glomerular kidney diseases remains largely obscure as suitable cell culture and animal models are lacking. In glomerular dise...

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Detalles Bibliográficos
Autores principales: Hagmann, Henning, Khayyat, Naghmeh Hassanzadeh, Oezel, Cem, Papadakis, Antonios, Kuczkowski, Alexander, Benzing, Thomas, Gulbins, Erich, Dryer, Stuart, Brinkkoetter, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688324/
https://www.ncbi.nlm.nih.gov/pubmed/36429053
http://dx.doi.org/10.3390/cells11223625