Tumor Microenvironment Immunosuppression: A Roadblock to CAR T-Cell Advancement in Solid Tumors

Chimeric antigen receptor (CAR) T cells are an exciting advancement in cancer immunotherapy, with striking success in hematological cancers. However, in solid tumors, the unique immunosuppressive elements of the tumor microenvironment (TME) contribute to the failure of CAR T cells. This review discu...

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Detalles Bibliográficos
Autores principales: Johnson, Abigail, Townsend, Michelle, O’Neill, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688327/
https://www.ncbi.nlm.nih.gov/pubmed/36429054
http://dx.doi.org/10.3390/cells11223626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688327/
https://www.ncbi.nlm.nih.gov/pubmed/36429054
http://dx.doi.org/10.3390/cells11223626

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