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Isolated BAP1 Genomic Alteration in Malignant Pleural Mesothelioma Predicts Distinct Immunogenicity with Implications for Immunotherapeutic Response

SIMPLE SUMMARY: Malignant Pleural Mesothelioma (MPM) is a highly aggressive, therapy-resistant cancer with a well-established inflammatory etiology and has no cure. Immune checkpoint inhibition (ICI) therapy has shifted treatment paradigms in many types of cancers, and recent clinical data have show...

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Detalles Bibliográficos
Autores principales: Osmanbeyoglu, Hatice Ulku, Palmer, Drake, Sagan, April, Sementino, Eleonora, Becich, Michael J., Testa, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688367/
https://www.ncbi.nlm.nih.gov/pubmed/36428720
http://dx.doi.org/10.3390/cancers14225626