ONX-0914 Induces Apoptosis and Autophagy with p53 Regulation in Human Glioblastoma Cells

SIMPLE SUMMARY: ONX-0914 (PR957) is a proteasome subunit beta type-8 (PSMB8)-selective inhibitor. Previous studies have shown that inhibiting PSMB8 expression in a glioblastoma reduces tumor progression and angiogenesis. This study shows that ONX-0914 inhibits glioblastoma cell proliferation and ind...

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Detalles Bibliográficos
Autores principales: Chang, Hsin-Han, Lin, Yi-Hsuan, Chen, Tzu-Min, Tsai, Yu-Ling, Lai, Chien-Rui, Tsai, Wen-Chiuan, Cheng, Yu-Chen, Chen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688407/
https://www.ncbi.nlm.nih.gov/pubmed/36428804
http://dx.doi.org/10.3390/cancers14225712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688407/
https://www.ncbi.nlm.nih.gov/pubmed/36428804
http://dx.doi.org/10.3390/cancers14225712

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