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2-Deoxyglucose, an Inhibitor of Glycolysis, Enhances the Oncolytic Effect of Coxsackievirus

SIMPLE SUMMARY: Oncolytic viruses infect tumor cells and trigger their death and elimination by the immune system. Several viral strains have been introduced into clinical practice. However, their therapeutic efficacy remains controversial. Here, we show that Coxsackievirus B5 (CVB5) causes the deat...

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Detalles Bibliográficos
Autores principales: Vorobyev, Pavel O., Kochetkov, Dmitry V., Chumakov, Peter M., Zakirova, Natalia F., Zotova-Nefedorova, Sofia I., Vasilenko, Konstantin V., Alekseeva, Olga N., Kochetkov, Sergey N., Bartosch, Birke, Lipatova, Anastasiya V., Ivanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688421/
https://www.ncbi.nlm.nih.gov/pubmed/36428704
http://dx.doi.org/10.3390/cancers14225611