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YAP Activation in Promoting Negative Durotaxis and Acral Melanoma Progression

Directed cell migration towards a softer environment is called negative durotaxis. The mechanism and pathological relevance of negative durotaxis in tumor progression still requires in-depth investigation. Here, we report that YAP promotes the negative durotaxis of melanoma. We uncovered that the Rh...

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Detalles Bibliográficos
Autores principales: Huang, Yuxing, Su, Jing, Liu, Jiayong, Yi, Xin, Zhou, Fang, Zhang, Jiaran, Wang, Jiaxiang, Meng, Xuan, Si, Lu, Wu, Congying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688430/
https://www.ncbi.nlm.nih.gov/pubmed/36428972
http://dx.doi.org/10.3390/cells11223543