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Gambogic Acid Induces Pyroptosis of Colorectal Cancer Cells through the GSDME-Dependent Pathway and Elicits an Antitumor Immune Response

SIMPLE SUMMARY: The treatment of colorectal cancer (CRC) is still a major challenge, and the manipulation of pyroptosis has become a novel therapeutic strategy for cancers. Gambogic acid (GA), a common traditional Chinese medicine, has been reported to be a potential agent for cancer treatment. Howe...

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Detalles Bibliográficos
Autores principales: Xu, Hanjie, Zhang, Danya, Wei, Rui, Zhou, Ying, Dai, Geyang, Li, Jie, Sun, Yue, Li, Fei, Xi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688471/
https://www.ncbi.nlm.nih.gov/pubmed/36428598
http://dx.doi.org/10.3390/cancers14225505