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S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression

NLRP3 inflammasome-dependent pyroptosis has been implicated in liver fibrosis progression. However, the definite intrahepatic cell types that undergo pyroptosis and the underlying mechanism as well as the clinical importance remain unclear. Here, augmented levels of pyroptosis-related indicators GSD...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Kong, Xuehua, You, Yan, Xiang, Linwei, Zhang, Yan, Wu, Rui, Zhou, Lan, Duan, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688473/
https://www.ncbi.nlm.nih.gov/pubmed/36429008
http://dx.doi.org/10.3390/cells11223579