SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice

Sirtuins (SIRT1–7 in mammals) are evolutionarily conserved nicotinamide adenine dinucleotide-dependent lysine deacetylases/deacylases that regulate fundamental biological processes including aging. In this study, we reveal that male Sirt7 knockout (KO) mice exhibited an extension of mean and maximum...

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Detalles Bibliográficos
Autores principales: Mizumoto, Tomoya, Yoshizawa, Tatsuya, Sato, Yoshifumi, Ito, Takaaki, Tsuyama, Tomonori, Satoh, Akiko, Araki, Satoshi, Tsujita, Kenichi, Tamura, Masaru, Oike, Yuichi, Yamagata, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688483/
https://www.ncbi.nlm.nih.gov/pubmed/36429037
http://dx.doi.org/10.3390/cells11223609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688483/
https://www.ncbi.nlm.nih.gov/pubmed/36429037
http://dx.doi.org/10.3390/cells11223609

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