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Effect of Dornase Alfa on the Lung Clearance Index in Children with Cystic Fibrosis: A Lesson from a Case Series

Background: Dornase alfa (DNase) is the only mucus-degrading agent that has proven efficacy in cystic fibrosis (CF). Few studies have evaluated the effects of DNase on the lung clearance index (LCI). We report the experience of two CF centers in which LCI monitoring was used to evaluate the efficacy...

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Detalles Bibliográficos
Autores principales: Terlizzi, Vito, Parisi, Giuseppe Fabio, Ferrari, Beatrice, Castellani, Chiara, Manti, Sara, Leonardi, Salvatore, Taccetti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688561/
https://www.ncbi.nlm.nih.gov/pubmed/36360353
http://dx.doi.org/10.3390/children9111625