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Targeting Leukemia-Initiating Cells and Leukemic Niches: The Next Therapy Station for T-Cell Acute Lymphoblastic Leukemia?
SIMPLE SUMMARY: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy arising from the aberrant proliferation of immature T-cell progenitors. Despite improved insights in genetic and biological characteristics of T-ALL, clinical therapy has remained largely similar. Recent studies...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688677/ https://www.ncbi.nlm.nih.gov/pubmed/36428753 http://dx.doi.org/10.3390/cancers14225655 |