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TRAIL-Based Therapies Efficacy in Pediatric Bone Tumors Models Is Modulated by TRAIL Non-Apoptotic Pathway Activation via RIPK1 Recruitment

SIMPLE SUMMARY: Osteosarcoma and Ewing sarcoma are the two most common malignant primary bone tumors occurring during childhood. These highly aggressive cancers are still clinically challenging, especially for recurrent/metastatic forms. Finding new therapeutic possibilities is critical to prolong s...

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Detalles Bibliográficos
Autores principales: Brion, Régis, Gantier, Malika, Biteau, Kevin, Taurelle, Julien, Brounais-Le Royer, Bénédicte, Verrecchia, Franck, Rédini, Françoise, Guiho, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688679/
https://www.ncbi.nlm.nih.gov/pubmed/36428719
http://dx.doi.org/10.3390/cancers14225627