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Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model

In dry age-related macular degeneration (AMD), inflammation plays a key role in disease pathogenesis. Innate immune cells such as microglia and neutrophils infiltrate the sub-retinal space (SRS) to induce chronic inflammation and AMD progression. But a major gap in our understanding is how these cel...

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Detalles Bibliográficos
Autores principales: Boyce, Maeve, Xin, Ying, Chowdhury, Olivia, Shang, Peng, Liu, Haitao, Koontz, Victoria, Strizhakova, Anastasia, Nemani, Mihir, Hose, Stacey, Zigler, J. Samuel, Campbell, Matthew, Sinha, Debasish, Handa, James T., Kaarniranta, Kai, Qian, Jiang, Ghosh, Sayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688699/
https://www.ncbi.nlm.nih.gov/pubmed/36428965
http://dx.doi.org/10.3390/cells11223535