Cargando…
Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
In dry age-related macular degeneration (AMD), inflammation plays a key role in disease pathogenesis. Innate immune cells such as microglia and neutrophils infiltrate the sub-retinal space (SRS) to induce chronic inflammation and AMD progression. But a major gap in our understanding is how these cel...
Autores principales: | Boyce, Maeve, Xin, Ying, Chowdhury, Olivia, Shang, Peng, Liu, Haitao, Koontz, Victoria, Strizhakova, Anastasia, Nemani, Mihir, Hose, Stacey, Zigler, J. Samuel, Campbell, Matthew, Sinha, Debasish, Handa, James T., Kaarniranta, Kai, Qian, Jiang, Ghosh, Sayan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688699/ https://www.ncbi.nlm.nih.gov/pubmed/36428965 http://dx.doi.org/10.3390/cells11223535 |
Ejemplares similares
-
A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD
por: Shang, Peng, et al.
Publicado: (2021) -
The role of lipocalin-2 in age-related macular degeneration (AMD)
por: Ghosh, Sayan, et al.
Publicado: (2020) -
Aberrant Akt2 signaling in the RPE may contribute to retinal fibrosis process in diabetic retinopathy
por: Daley, Rachel, et al.
Publicado: (2023) -
Mitophagy in Astrocytes Is Required for the Health of Optic Nerve
por: Yazdankhah, Meysam, et al.
Publicado: (2023) -
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy
por: Liu, Haitao, et al.
Publicado: (2022)