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Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts
SIMPLE SUMMARY: Glioblastoma (GBM) is the most common and aggressive adult-type diffusely infiltrating glioma. These tumors invariably develop resistance to standard treatment with radiation and temozolomide, leading to recurrence and almost always fatal outcomes. In vivo models of such recurrences...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688760/ https://www.ncbi.nlm.nih.gov/pubmed/36428586 http://dx.doi.org/10.3390/cancers14225494 |