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Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts

SIMPLE SUMMARY: Glioblastoma (GBM) is the most common and aggressive adult-type diffusely infiltrating glioma. These tumors invariably develop resistance to standard treatment with radiation and temozolomide, leading to recurrence and almost always fatal outcomes. In vivo models of such recurrences...

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Detalles Bibliográficos
Autores principales: McCord, Matthew, Bartom, Elizabeth, Burdett, Kirsten, Baran, Aneta, Eckerdt, Frank D., Balyasnikova, Irina V., McCortney, Kathleen, Sears, Thomas, Cheng, Shi-Yuan, Sarkaria, Jann N., Stupp, Roger, Heimberger, Amy B., Ahmed, Atique, James, Charles David, Horbinski, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688760/
https://www.ncbi.nlm.nih.gov/pubmed/36428586
http://dx.doi.org/10.3390/cancers14225494