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The Somatic Mutation Landscape of UDP-Glycosyltransferase (UGT) Genes in Human Cancers

SIMPLE SUMMARY: The human UDP-glycosyltransferase (UGT) superfamily is involved in the metabolism of numerous anticancer drugs and endobiotic signaling molecules with pro/anti-cancer activities. Previous studies have shown abundant expression of UGT genes in many human cancers, indicative of the act...

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Detalles Bibliográficos
Autores principales: Hu, Dong Gui, Marri, Shashikanth, Hulin, Julie-Ann, McKinnon, Ross A., Mackenzie, Peter I., Meech, Robyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688768/
https://www.ncbi.nlm.nih.gov/pubmed/36428799
http://dx.doi.org/10.3390/cancers14225708