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The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids

Intrauterine infections during pregnancy by herpes simplex virus (HSV) can cause significant neurodevelopmental deficits in the unborn/newborn, but clinical studies of pathogenesis are challenging, and while animal models can model some aspects of disease, in vitro studies of human neural cells prov...

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Detalles Bibliográficos
Autores principales: D’Aiuto, Leonardo, Caldwell, Jill K., Wallace, Callen T., Grams, Tristan R., Wesesky, Maribeth A., Wood, Joel A., Watkins, Simon C., Kinchington, Paul R., Bloom, David C., Nimgaonkar, Vishwajit L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688774/
https://www.ncbi.nlm.nih.gov/pubmed/36428968
http://dx.doi.org/10.3390/cells11223539