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Differential Levels of Tryptophan–Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy

Glutamate-receptor-mediated hyperexcitability contributes to seizure generation in temporal lobe epilepsy (TLE). Tryptophan–kynurenine pathway (TKP) metabolites regulate glutamate receptor activity under physiological conditions. This study was designed to investigate alterations in the levels of TK...

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Detalles Bibliográficos
Autores principales: Dey, Soumil, Dubey, Vivek, Dixit, Aparna Banerjee, Tripathi, Manjari, Chandra, Poodipedi Sarat, Banerjee, Jyotirmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688794/
https://www.ncbi.nlm.nih.gov/pubmed/36428989
http://dx.doi.org/10.3390/cells11223560