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o-Vanillin Modulates Cell Phenotype and Extracellular Vesicles of Human Mesenchymal Stem Cells and Intervertebral Disc Cells

Human mesenchymal stem cell (hMSC) and extracellular vesicle (EV) therapy is a promising treatment for discogenic low back pain (LBP). Although promising, major obstacles remain to be overcome. Cellular senescence reduces self-renewal and multipotent potentials, and the senescence-associated secreto...

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Detalles Bibliográficos
Autores principales: Li, Li, Sheng, Kai, Mannarino, Matthew, Jarzem, Peter, Cherif, Hosni, Haglund, Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688801/
https://www.ncbi.nlm.nih.gov/pubmed/36429018
http://dx.doi.org/10.3390/cells11223589