UCHL5 Promotes Proliferation and Migration of Bladder Cancer Cells by Activating c-Myc via AKT/mTOR Signaling

SIMPLE SUMMARY: In this study, we demonstrate that ubiquitin C-terminal hydrolase-L5 (UCHL5), a member of the DUBs family, promotes the growth and migration of bladder cancer cells and facilitates tumor growth in vitro. Using shRNA-mediated knockdown and overexpression of UCHL5, we confirm that UCHL...

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Detalles Bibliográficos
Autores principales: Cao, Yuanfei, Yan, Xin, Bai, Xiaojie, Tang, Feng, Si, Penghui, Bai, Can, Tuoheti, Kuerban, Guo, Linfa, Yisha, Zuhaer, Liu, Tao, Liu, Tongzu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688806/
https://www.ncbi.nlm.nih.gov/pubmed/36428630
http://dx.doi.org/10.3390/cancers14225538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688806/
https://www.ncbi.nlm.nih.gov/pubmed/36428630
http://dx.doi.org/10.3390/cancers14225538

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