Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness

SIMPLE SUMMARY: Cancer cells gaining stem cell gene signatures has been deemed as the root of cancers. Blocking the driver genes that control cancer stemness will lead to effective tumor suppression. Lin28 is a stemness driver gene that exerts its tumor-promoting activity through its RNA binding cap...

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Detalles Bibliográficos
Autores principales: Radaeva, Mariia, Ho, Chia-Hao, Xie, Ning, Zhang, Sijie, Lee, Joseph, Liu, Liangliang, Lallous, Nada, Cherkasov, Artem, Dong, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688808/
https://www.ncbi.nlm.nih.gov/pubmed/36428779
http://dx.doi.org/10.3390/cancers14225687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688808/
https://www.ncbi.nlm.nih.gov/pubmed/36428779
http://dx.doi.org/10.3390/cancers14225687

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