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Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness
SIMPLE SUMMARY: Cancer cells gaining stem cell gene signatures has been deemed as the root of cancers. Blocking the driver genes that control cancer stemness will lead to effective tumor suppression. Lin28 is a stemness driver gene that exerts its tumor-promoting activity through its RNA binding cap...
Autores principales: | Radaeva, Mariia, Ho, Chia-Hao, Xie, Ning, Zhang, Sijie, Lee, Joseph, Liu, Liangliang, Lallous, Nada, Cherkasov, Artem, Dong, Xuesen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688808/ https://www.ncbi.nlm.nih.gov/pubmed/36428779 http://dx.doi.org/10.3390/cancers14225687 |
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