Further Extension of Lifespan by Unc-43/CaMKII and Egl-8/PLCβ Mutations in Germline-Deficient Caenorhabditis elegans

Reduction of insulin/insulin-like growth factor 1 (IGF1) signaling (IIS) promotes longevity across species. In the nematode Caenorhabditis elegans, ablation of germline stem cells (GSCs) and activity changes of the conserved signaling mediators unc-43/CaMKII (calcium/calmodulin-dependent kinase type...

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Detalles Bibliográficos
Autores principales: Mack, Hildegard I. D., Buck, Laura G., Skalet, Sonja, Kremer, Jennifer, Li, Hao, Mack, Elisabeth K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688844/
https://www.ncbi.nlm.nih.gov/pubmed/36428956
http://dx.doi.org/10.3390/cells11223527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688844/
https://www.ncbi.nlm.nih.gov/pubmed/36428956
http://dx.doi.org/10.3390/cells11223527

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