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Overexpression of RCAN1, a Gene on Human Chromosome 21, Alters Cell Redox and Mitochondrial Function in Enamel Cells

The regulator of calcineurin (RCAN1) has been implicated in the pathogenesis of Down syndrome (DS). Individuals with DS show dental abnormalities for unknown reasons, and RCAN1 levels have been found to be elevated in several tissues of DS patients. A previous microarray analysis comparing cells of...

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Detalles Bibliográficos
Autores principales: Li, Yi, Costiniti, Veronica, Souza Bomfim, Guilherme H., Neginskaya, Maria, Son, Ga-Yeon, Rothermel, Beverly, Pavlov, Evgeny, Lacruz, Rodrigo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688881/
https://www.ncbi.nlm.nih.gov/pubmed/36429004
http://dx.doi.org/10.3390/cells11223576