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Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway

SIMPLE SUMMARY: Multiple myeloma (MM) is a cancer of white blood cells known as plasma cells. It is hard to treat cancer, thus requires new treatments. Herein, a plant extracted compound, guggulsterone (GS), has been investigated for its anticancer activity in MM cells. The results from this study r...

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Detalles Bibliográficos
Autores principales: Akhtar, Sabah, Zarif, Lubna, Kuttikrishnan, Shilpa, Prabhu, Kirti S., Patil, Kalyani, Nisar, Sabah, Abou-Saleh, Haissam, Merhi, Maysaloun, Dermime, Said, Bhat, Ajaz A., Uddin, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688888/
https://www.ncbi.nlm.nih.gov/pubmed/36428714
http://dx.doi.org/10.3390/cancers14225621