ERK Inhibitor Ulixertinib Inhibits High-Risk Neuroblastoma Growth In Vitro and In Vivo

SIMPLE SUMMARY: Neuroblastoma (NB) is the most common extracranial solid tumor in children, and the majority of patients with high-risk disease are unable to be cured. There is an urgent need to design novel therapeutics for NB patients. In NB, the RAS-MAPK pathway plays a crucial role in essential...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Zhao, Yanling, Choi, Jongmin, Shi, Zhongcheng, Guo, Linjie, Elizarraras, John, Gu, Andy, Cheng, Feng, Pei, Yanxin, Lu, Dai, Fabbri, Muller, Agarwal, Saurabh, Zhang, Chunchao, Jung, Sung Yun, Foster, Jennifer H., Yang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688897/
https://www.ncbi.nlm.nih.gov/pubmed/36428626
http://dx.doi.org/10.3390/cancers14225534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688897/
https://www.ncbi.nlm.nih.gov/pubmed/36428626
http://dx.doi.org/10.3390/cancers14225534

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