Opposing Roles of IGFBP-3 and Heparanase in Regulating A549 Lung Cancer Cell Survival

In this study, we examined the roles of heparanase and IGFBP-3 in regulating A549 and H1299 non-small-cell lung cancer (NSCLC) survival. We found that H1299 cells, known to be p53-null with no expression of IGFBP-3, had higher heparanase levels and activity and higher levels of heparan sulfate (HS)...

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Detalles Bibliográficos
Autores principales: Al Khashali, Hind, Wareham, Jadziah, Ray, Ravel, Haddad, Ben, Coleman, Kai-Ling, Ranzenberger, Robert, McCombs, Patrick, Guthrie, Jeffrey, Heyl, Deborah, Evans, Hedeel Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688904/
https://www.ncbi.nlm.nih.gov/pubmed/36428962
http://dx.doi.org/10.3390/cells11223533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688904/
https://www.ncbi.nlm.nih.gov/pubmed/36428962
http://dx.doi.org/10.3390/cells11223533

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