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The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons

Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic neurotransmission, synaptic plasticity, and memory flexibility. Nevertheless, Panx1-...

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Detalles Bibliográficos
Autores principales: Flores-Muñoz, Carolina, García-Rojas, Francisca, Pérez, Miguel A., Santander, Odra, Mery, Elena, Ordenes, Stefany, Illanes-González, Javiera, López-Espíndola, Daniela, González-Jamett, Arlek M., Fuenzalida, Marco, Martínez, Agustín D., Ardiles, Álvaro O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688914/
https://www.ncbi.nlm.nih.gov/pubmed/36429074
http://dx.doi.org/10.3390/cells11223646