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The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons
Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic neurotransmission, synaptic plasticity, and memory flexibility. Nevertheless, Panx1-...
Autores principales: | Flores-Muñoz, Carolina, García-Rojas, Francisca, Pérez, Miguel A., Santander, Odra, Mery, Elena, Ordenes, Stefany, Illanes-González, Javiera, López-Espíndola, Daniela, González-Jamett, Arlek M., Fuenzalida, Marco, Martínez, Agustín D., Ardiles, Álvaro O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688914/ https://www.ncbi.nlm.nih.gov/pubmed/36429074 http://dx.doi.org/10.3390/cells11223646 |
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