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Thermosensitive In Situ Gels for Joint Disorders: Pharmaceutical Considerations in Intra-Articular Delivery

The intra-articular administration of conventional drug solutions or dispersions in joint diseases such as osteoarthritis has a relatively short retention time and, therefore, limited therapeutic effect. Thermosensitive polymer solutions that exhibit a sol–gel phase transition near body temperature...

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Detalles Bibliográficos
Autores principales: Koland, Marina, Narayanan Vadakkepushpakath, Anoop, John, Anish, Tharamelveliyil Rajendran, Arunraj, Raghunath, Indu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689403/
https://www.ncbi.nlm.nih.gov/pubmed/36354630
http://dx.doi.org/10.3390/gels8110723