Targeting Mitochondrial ROS Production to Reverse the Epithelial-Mesenchymal Transition in Breast Cancer Cells

Experimental evidence implicates reactive oxygen species (ROS) generation in the hypoxic stabilization of hypoxia-inducible factor (HIF)-1α and in the subsequent expression of promoters of tumor invasiveness and metastatic spread. However, the role played by mitochondrial ROS in hypoxia-induced Epit...

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Detalles Bibliográficos
Autores principales: Monti, Elena, Mancini, Alessandro, Marras, Emanuela, Gariboldi, Marzia Bruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689492/
https://www.ncbi.nlm.nih.gov/pubmed/36354671
http://dx.doi.org/10.3390/cimb44110359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689492/
https://www.ncbi.nlm.nih.gov/pubmed/36354671
http://dx.doi.org/10.3390/cimb44110359

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