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High Plasma Levels of Activated Factor VII-Antithrombin Complex Point to Increased Tissue Factor Expression in Patients with SARS-CoV-2 Pneumonia: A Potential Link with COVID-19 Prothrombotic Diathesis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent of coronavirus disease 2019 (COVID-19), in which coagulation abnormalities and endothelial dysfunction play a key pathogenic role. Tissue factor (TF) expression is triggered by endothelial dysfunction. Activated factor...

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Detalles Bibliográficos
Autores principales: Martinelli, Nicola, Rigoni, Anna Maria, De Marchi, Sergio, Osti, Nicola, Donini, Martino, Montagnana, Martina, Castagna, Annalisa, Pattini, Patrizia, Udali, Silvia, De Franceschi, Lucia, Tinazzi, Elisa, Mazzi, Filippo, Moruzzi, Sara, Argentino, Giuseppe, Delfino, Lorenzo, Sartori, Giulia, Azzini, Anna Maria, Tacconelli, Evelina, Van Dreden, Patrick, Lippi, Giuseppe, Girelli, Domenico, Olivieri, Oliviero, Friso, Simonetta, Pizzolo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689539/
https://www.ncbi.nlm.nih.gov/pubmed/36428852
http://dx.doi.org/10.3390/diagnostics12112792