Partial Disturbance of Microprocessor Function in Human Stem Cells Carrying a Heterozygous Mutation in the DGCR8 Gene

Maturation of microRNAs (miRNAs) begins by the “Microprocessor” complex, containing the Drosha endonuclease and its partner protein, "DiGeorge Syndrome Critical Region 8" (DGCR8). Although the main function of the two proteins is to coordinate the first step of precursor miRNAs formation,...

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Detalles Bibliográficos
Autores principales: Reé, Dóra, Fóthi, Ábel, Varga, Nóra, Kolacsek, Orsolya, Orbán, Tamás I., Apáti, Ágota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689658/
https://www.ncbi.nlm.nih.gov/pubmed/36360162
http://dx.doi.org/10.3390/genes13111925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689658/
https://www.ncbi.nlm.nih.gov/pubmed/36360162
http://dx.doi.org/10.3390/genes13111925

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