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A multifunctional oxidative stress nanoamplifier with ROS amplification and GSH exhaustion for enhanced chemodynamic therapy

Chemodynamic therapy (CDT) eradicates tumors by intratumoral catalytic chemical reaction and subsequently disrupts redox homeostasis, which shows tumor specific reactive oxygen species (ROS)-mediated therapy. However, insufficient ROS generation and high levels of glutathione (GSH) in cancer cells h...

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Detalles Bibliográficos
Autores principales: Zhong, Wenzhao, Guo, Feng, Chen, Fangman, Law, Man-Kay, Lu, Jun, Shao, Dan, Yu, Hua, Chan, Ging, Chen, Meiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689698/
https://www.ncbi.nlm.nih.gov/pubmed/36438812
http://dx.doi.org/10.3389/fphar.2022.1044083